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The story

Driven by a high ambition and a great motivation, the idea of MOGGE foundation was first proposed by Dr. Sherif Shazly, an Egyptian obstetrician and gynecologist who has gained research and clinical experience at Assiut University, Egypt and Mayo Clinic, Rochester, USA. Dr. Shazly brought his Egyptian background to the USA where he was able to compare and recognize not only the magnitude of the gap, but also the most challenging aspects that create most of this gap. He realized that equipment, funds and technology play a role in the equation. However, there is also a major role to knowledge and development; a role that is usually overlooked when comparing a developed country to a developing country. Money and resources seem to be the easiest answer and the most challenging to deal with. Nevertheless, there is a lot that can be fixed by improving medical knowledge, following evidence-based medicine, expanding research, and improving medical education.

 

During his journey, Dr. Shazly also noticed that medicine is as wide as life itself. Everybody is different and there is no way our genes, which encode our interests, strengths and weakness, will all fit to one pathway. In other words, medicine can adopt all our talents even if they do not look directly related to medicine. Your talents are your strengths and you have to learn about them, explore them, and use them in your career to excel and enjoy your work. Some people even regret choosing medicine since they think there is a better fit for them while actually, there is a lot you can do in medicine. If you enjoy teaching, you should expose yourself to medical education. If you are a little uncomfortable with patient contact and you prefer introvert thinking, you should know more about research. If you like to design or paint, you can use that to deliver clinical messages or produce your books or videos. If you like business, you have a place. There are hundreds of examples for that. However, most doctors do not have the opportunity to test their skills and learn more about themselves.

 

In 2017, 3 years after arriving to the USA, Dr. Shazly decided to begin with a small nucleus before trying to go bigger. His idea was to communicated with medical students first. He always believes that medical students have the most underestimated protentional in the world being excited to learn, easier to teach, energetic, creative, and ambitious. That was actually a good decision since many of the students, who are now becoming interns, are still a part of the foundation to date such as Dr. Ahmad Radwan and Dr. Nermeen Bahaa. Although the start was just limited to a small research group, this group has been strongly connected as a family, believing in their dream to expand the project, knowing that it will take much time and effort. 

The actual start was in 2019, when Dr. Shazly managed to meet the team for the first time in Egypt, where it was clear that all members were strongly connected to the project and willing to continue. By that time, Dr. Shazly and his colleagues decided to move on the real dream, and PROJECT:EXTRME 2020, a 5-year project, was first launched. The project has the goal of transitioning the current nucleus to an international academic and clinical institute that serves young OBGYN doctors and enhance medical research and technology in Egypt and the Middle-East. Interviews were held to recruit more members and senior OBGYN doctors from USA, UK, and Europe were invited to reinforce this ongoing work.

 

Although the year 2020 was not the happiest to earth, it met all the promises to the MOGGE foundation. It was a huge challenge to move on while the world has been facing such dramatic events. Nevertheless, the amazing MOGGE team managed to take off to the horizon and in one year, MOGGE foundation was able to run 3 research projects, initiate practice guidelines for the Middle-East region, start its first multicenter international study in collaboration with 11 centers from 9 countries, start its first clinical trial, initiate the first specialized OBGYN-based artificial intelligence unit (AI) in Egypt. The same year witnessed the completion of the first AI project and the launch of MOGGESoft, a software department affiliated by MOGGE foundation, which released 2 versions of an OBGYN clinical software bundle so far.

In October 2022 and as planned, MOGGE foundation has successfully transitioned to the current name "MCOG", which goes with the planned expansion of the role of the foundation to serve broader educational, research and clinical objectives in collaboration with doctors in the Middle East and worldwide. 

  

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The photo was taken when Dr. Shazly and his colleagues first met in Egypt in 2019 to discuss project:extreme.

 

From Left to right: Heba Nashaat, Menna Nashaat, Mohamed Attyia, Sherif Shazly, Ahmad Radwan, Ahmed Salah, Ahmed Kamel, Mostafa Hussein, Ahmed Yassein, Nermeen Bahaa, Fatma Atef, Yasmin Ismail

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The photo was taken after the first interview in December 2019

From left to right: Mostafa Hussein, Ahmed Yassein, Sherif Shazly, Heba Nashaat, Yasmin Ismail, Menna Nashaat, Fatma Atef, Gena Elassal, Nermeen Bahaa

Who are we?

We are a group of medical students, interns and young doctors, working under mentorship of senior OBGYN doctors, of both Middle-Eastern and Western research and clinical background, who design and supervise ongoing projects and initiate future directives of the foundation with the ultimate goal of enhancing research, education, and practice in the field of OBGYN in low-resource countries.

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Structure

MOGGE foundation structure starts with a president, and 2 vice presidents (administrative and scientific). The main structure is divided into:

  • Research and innovations office: which is responsible for research projects and research fellowship program of the new comers

  • Practice office: which is responsible for developing MOGGE practice guidelines  

  • Educational office: which is responsible for production of educational material including books, videos and more

  • Multicenter study (MCS) unit: which designs and conducts multicenter studies in collaboration with our international partners

  • RCT unit: specialized in clinical trials 

  • Statistics department: which performs the statistics related to any ongoing research project

  • AI unit: which designs and conducts AI-related products using machine learning algorithms

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ِ A photo from February 2020 on celebrating the publication of the first MOGGE practice guideline

Objectives
  • Bridging the gap between developed and developing countries in the field of OBGYN by reinforcing the value of knowledge and research and delivering them in the most accessible way to the hands of all doctors.

  • Providing an equal chance of robust training to all young OBGYN doctors by using all means of medical education.

  • Creating a platform to medical students and young doctors to learn new skills, develop their abilities and invest their potentials in different aspects of medicine, and expand their knowledge to younger generations as they grow up.

  • Actively presenting the Middle-East in the field of high-quality research and advanced AI technology.

  • Serving our community in all aspects that can improve the service provided to our patients.  

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ِ A photo from February 2020 from class 2020 orientation session

Achievements

Research Office:

  • AlMahdy AM, Elassall GM, Abdelbadee AY, Abd-Elkariem AY, Atef F, Ahmed IA, Sayed EG, Salah MA, Ali AK, Ragab EY, Abd Elazeem HA. Prognostic value of systematic lymphadenectomy in patients with ovarian cancer: A systematic review and meta-analysis. European Journal of Obstetrics & Gynecology and Reproductive Biology. 2021 Dec 1;267:179-85.

  • Abd Elazeem HA, Saad MM, Ahmed IA, Sayed EG, AlMahdy AM, Atef F, Elassall GM, Ashraf Salah M, Ali AK, Ragab EY, Shazly SA. High‐intensity focused ultrasound in management of placenta accreta spectrum: A systematic review. International Journal of Gynecology & Obstetrics. 2020 Dec;151(3):325-32.

 

  • Michael A, Radwan AA, Ali AK, Abd-Elkariem AY, Shazly SA, Obstetrics ME, Group GG. Use of antenatal fluorinated corticosteroids in management of congenital heart block: systematic review and meta-analysis. European journal of obstetrics & gynecology and reproductive biology: X. 2019 Oct 1;4:100072.

  • Esraa G. Sayed; Fatma Atef; Mohamed Ashraf Salah; AlBatool M. AlMahdy; Gena M. Elassall; Ahmad A. Radwan; Islam A. Ahmed; Ahmed S. Sedik; Esraa Y Ragab; Hossam Aldein S. Abd Elazeem; Mahmoud M. Saad;Sherif Shazly. Management of recurrent stress urinary incontinence in women: A systematic review and meta-analysis (under reviewing)

  • MOGGE research fellowship program, formally launched in 2021

Practice Office:

  • Shazly SA, Shawki AA, Ahmed MM, Monib FA, Radwan AA, Sedik AS, Said AE, Ali SS, Abouzeid MH, Sayed EG, Nassr AA. Middle-East OBGYN graduate education (MOGGE) foundation practice guidelines: use of labor charts in management of labor. Practice guideline no. 04-O-21. The Journal of Maternal-Fetal & Neonatal Medicine. 2021 Jul 13:1-0.

  • Sherif A Shazly, Ahmad A Radwan, Abdelrahman A Shawki, Aliaa E Said, Yasmin I Mohamed, Heba N Hemdan, Menna N Hemdan, Norhan G Mohamed, Rania I Adam, Ahmed A Nassr, Nashwa A Eltaweel, Ismet Hortu, Amr Shehata, Mohamed S Abdo, Hajer Y Moustafa, Ahmed Yassien Abd-Elkariem, Shimaa Salah Ali, Nermeen B Ahmed, Esraa M Hosny, Mostafa H Abouzeid, Middle-East OBGYN Graduate Education (MOGGE) Foundation practice guidelines: prevention of group B Streptococcus infection in pregnancy and in newborn. Practice guideline no. 02-O-20. J Matern Fetal Neonatal Med. 2021 Feb 24;1-12. 

  • Shazly SA, Ahmed IA, Radwan AA, Abd-Elkariem AY, El-Dien NB, Ragab EY, Abouzeid MH, Shams AH, Ali AK, Hemdan HN, Hemdan MN. Middle-East OBGYN Graduate Education (MOGGE) Foundation Practice Guidelines: Prelabor rupture of membranes; Practice guideline No. 01-O-19. Journal of global health. 2020 Jun;10(1).

  • Sherif A Shazly, Ahmad A Radwan, Abdelrahman A Shawki, Aliaa E Said, Yasmin I Mohamed, Heba N Hemdan, Menna N Hemdan, Norhan G Mohamed, Rania I Adam, Ahmed A Nassr, Nashwa A Eltaweel, Ismet Hortu, Amr Shehata, Mohamed S Abdo, Hajer Y Moustafa, Ahmed Yassien Abd-Elkariem, Shimaa Salah Ali, Nermeen B Ahmed, Esraa M Hosny, Mostafa H Abouzeid. Middle-East OBGYN Graduate Education (MOGGE) Foundation Practice Guidelines: Diagnostic approach to pregnancy of unknown location. Practice Guideline No. 03-O-21 (under reviewing)

 

Educational Office

  • Placenta accreta spectrum - Springer nature 2022 (in press)

  • MRCOG part 2: Essential revision guide - Springer Nature 2022

  • 70 online free lectures (obstetrics series, general gynecology series, urogynecology series, surgeon's corner, OBGYN case series)

Multicenter study (MCS) unit

  • PAS-ID (Placenta accreta spectrum international database) project: a database of 727 patients with placenta accreta from 9 countries (database completed)

  1. Shazly SA, Hortu I, Shih JC, Melekoglu R, Fan S, Ahmed FU, Karaman E, Fatkullin I, Pinto PV, Irianti S, Tochie JN. Prediction of success of uterus‐preserving management in women with placenta accreta spectrum (CON‐PAS score): A multicenter international study. International Journal of Gynecology & Obstetrics. 2021 Aug;154(2):304-11.

  2. ​​Shazly SA, Hortu I, Shih JC, Melekoglu R, Fan S, Ahmed FU, Karaman E, Fatkullin I, Pinto PV, Irianti S, Tochie JN. Prediction of success of uterus preserving management in women with placenta accreta spectrum (CON-PAS score): A multicenter international study. Int. j. gynaecol. obstet. 2020.​ 

  • PAR-validation international study: an ongoing international study to validate prediction models from previous studies:

Shazly SA, Anan MA, Makukhina TB, Melekoglu R, Ahmed FU, Pinto PV, Takahashi H, Ahmed NB, Sayed EG, Elassall GM, Said AE. Placenta accreta risk—antepartum score in predicting clinical outcomes of placenta accreta spectrum: A multicenter validation study. International Journal of Gynecology & Obstetrics. 2021 Oct 21.

  • Endometrial Cancer International Database (EC-ID) project: an international database of endometrial cancer patients is in the preparatory stage 

Statistics department 

  • Comparing conservative to radical management in PAS patients: ongoing project

  • Immediate vs. delayed cord clamping in PAS patients: ongoing project 

AI unit

  • Shazly S, Hortu I, Shih JC, Melekoglu R, Fan S, Karaman E, Fatkullin I, Pinto P, Irianti S, Tochie J, Abdelbadie A. Prediction of Clinical Outcomes in Women with Placenta Accreta Spectrum Using Machine Learning Models: An International Multicenter Study (under reviewing)

  • MOGGE PAR-A and PAR-P scores: a software driven from a machine learning model that predicts clinical outcomes of PAS

  • Launching OBG-AI21: an initiative to create an international network to support AI projects related to OBGYN 

 

MOGGESOFT

  • MOGGE E-OBGYN bundle versions 1 and 2: a bundle of 7 PC applications that assists clinicians to practice evidence-based medicine without effort while seeing their patients and documenting their visits 

  • MOGGE CON-PAS score: an application that predicts probability of success of conservative management in patients with PAS based on results from a previous study 

 

 

 

 

 

 

 

 

 

 

 

Others

  • CON-PAS registry: MOGGE foundation has created a registry of all studies that reported conservative management of PAS to be used as a reference to those who want to track current evidence on their implementation 

  • Prev-GBS campaign: a national campaign, launched in 2020 to raise awareness on importance of GBS screening and facilitate connection between private practice and labs

  • Initiating PLUS clinical trial for management of second stage cesarean section in Aswan University, Egypt

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First published MOGGE foundation practice guideline

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PAS-ID project completed in 2020

CON-PAS score application for prediction of success of conservative management in patients with PAS

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MOGGE OBGYN clinical bundle of applications by MOGGESoft

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MOGGESoft first machine learning-based application

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MOGGE AI unit (logo)

CON-PAS registry of studies that appraise conservative management options of PAS

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PREV-GBS campaign: raising awareness regarding GBS infection and screening

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